Hyssogenix

Services

We offer services to dental clinics in the field of genetics and microbiology.

Accurate diagnosis of oral candidiasis using PCR

Oral candidiasis is a common infection of the oral mucosa, particularly in immunocompromised patients, those with removable prostheses, xerostomia, or undergoing prolonged treatment with antibiotics or corticosteroids. Although it is often treated empirically, identifying the exact Candida species is essential in recurrent or treatment-resistant cases.

At Hyssogenix, we offer a real-time PCR molecular analysis that enables the precise detection and quantification of the main species involved in oral candidiasis.

Accurate diagnosis of oral candidiasis using PCR

Oral candidiasis is a common infection of the oral mucosa, particularly in immunocompromised patients, those with removable prostheses, xerostomia, or undergoing prolonged treatment with antibiotics or corticosteroids. Although it is often treated empirically, identifying the exact Candida species is essential in recurrent or treatment-resistant cases.

At Hyssogenix, we offer a real-time PCR molecular analysis that enables the precise detection and quantification of the main species involved in oral candidiasis.

When is this analysis indicated?
  • Whitish or erythematous lesions, or persistent burning sensation in the oral mucosa
  • Lack of response to common topical antifungals
  • Immunocompromised or diabetic patients, or those with xerostomia
  • Recurrent or treatment-refractory candidiasis

 

📌 Also useful for differential diagnosis against leukoplakia, lichen planus, or atrophic glossitis.

Candida species detected by PCR
  • Candida albicans (most frequent)
  • Candida glabrata (fluconazole-resistant)
  • Candida tropicalis
  • Candida krusei (resistant to multiple azoles)
  • Candida parapsilosis

 

🧬 Knowing the species allows the choice of the most effective antifungal and avoids unnecessary treatments.

Clinical application of the test
  • Optimizes antifungal treatment selection
  • Avoids empirical prescription in complex patients
  • Facilitates microbiological follow-up after treatment
  • Reduces the risk of resistance and overtreatment
Advantages of the Hyssogenix oral candidiasis test
  • Results in < 72 h
  • High sensitivity and specificity
  • Quantification of fungal load
  • Painless collection using oral swab

 

📦 An objective and rapid diagnostic tool for the clinical management of Candida infections.

Frequently Asked Questions about the Oral Candida PCR Test

When is this analysis recommended?
In cases of persistent lesions, recurrent candidiasis, or immunocompromised patients.

Which Candida species does the test detect?
Candida albicans, Candida glabrata, Candida tropicalis, Candida krusei, and Candida parapsilosis.

Why is it important to know the species?
Because some are resistant to common antifungals. Identifying the species allows the selection of the most effective treatment.

How is the sample collected?
With a swab rubbed over the oral mucosa for 1 minute. Simple and painless.

How long do the results take?
Less than 72 hours after receipt in the laboratory.

What advantages does it provide compared to conventional culture?
Greater sensitivity, species-specific identification, speed, and detection of resistance.

More precise treatments for your clients

More precise treatments for your clients

We help you to make your diagnoses more accurate and provide the most suitable treatment for your patients’ pathologies.
Improve the effectiveness of your practice

Improve the effectiveness of your practice

We take care of everything: we collect your test, analyse it and send it back to your practice.
We protect your patients

We protect your patients

We prioritise your anonymity, working with anonymised data (sample codes), never with personal data.