Hyssogenix

Services

We offer services to dental clinics in the field of genetics and microbiology.

Precision microbiological diagnosis for bad breath

Bad breath—or halitosis—is usually caused by anaerobic bacteria present in the oral cavity that release volatile sulfur compounds (VSCs), responsible for the unpleasant odor. At Hyssogenix, we use real-time PCR to determine whether these bacteria are present and in what concentration, enabling identification of the microbiological cause and clinical monitoring after treatment.

Precision microbiological diagnosis for bad breath

Bad breath—or halitosis—is usually caused by anaerobic bacteria present in the oral cavity that release volatile sulfur compounds (VSCs), responsible for the unpleasant odor. At Hyssogenix, we use real-time PCR to determine whether these bacteria are present and in what concentration, enabling identification of the microbiological cause and clinical monitoring after treatment.

Why perform this analysis in patients with halitosis?
  • Accurate diagnosis: differentiates between halitosis of oral origin and other possible causes (digestive or systemic), and helps identify conditions such as incipient periodontitis.
  • Objective monitoring: allows comparison of bacterial load before and after treatment.
  • Avoids unnecessary treatments: if no relevant bacteria are detected, indiscriminate use of mouthwashes or antibiotics is avoided, preserving the balance of the oral microbiome.
Bacteria analyzed by PCR

The panel includes key microorganisms involved in halitosis and periodontal pathology:

  • Porphyromonas gingivalis
  • Treponema denticola
  • Tannerella forsythia
  • Prevotella intermedia
  • Fusobacterium nucleatum
  • Solobacterium moorei

 

These species are implicated in both chronic tongue-related halitosis and subclinical periodontal pathologies.

Clinical application

Although some of these bacteria may respond to antibiotics, the usual approach is mechanical or antiseptic (chlorhexidine). Antibiotic therapy is considered only when there is a high concentration of periodontopathogenic bacteria and always under clinical judgment.

The Hyssogenix report allows the dentist to:

  • Act on the basis of objective data.
  • Apply targeted treatments.
  • Improve patient experience and prognosis.
Advantages of the Hyssogenix halitosis test
  • Results in less than 72 hours
  • High sensitivity and specificity
  • Diagnostic value for hidden periodontal risk
  • Ideal for follow-ups and evolutionary control

 

📦 Provide your patients with a scientifically based halitosis diagnosis and strengthen your treatment plan with Hyssogenix.

Frequently Asked Questions about the Halitosis Analysis

Which bacteria are associated with bad breath?
Mainly Solobacterium moorei, Fusobacterium nucleatum, and other anaerobes that generate volatile sulfur compounds (VSCs).

Does the test differentiate between oral halitosis and other causes?
Yes. If the test is negative, oral causes can be ruled out, and systemic, digestive, or metabolic causes can be investigated.

How long do the results take?
Less than 72 hours from sample reception.

Can the test be repeated after treatment?
Yes. It makes it possible to verify whether the treatment has reduced the bacterial load.

How is the sample collected?
With paper points placed in the subgingival area, the main reservoir of anaerobic bacteria that produce VSCs.

Is antibiotic treatment recommended if the result is positive?
Only if highly pathogenic species such as P. gingivalis are detected, and always under professional criteria.

More precise treatments for your clients

More precise treatments for your clients

We help you to make your diagnoses more accurate and provide the most suitable treatment for your patients’ pathologies.
Improve the effectiveness of your practice

Improve the effectiveness of your practice

We take care of everything: we collect your test, analyse it and send it back to your practice.
We protect your patients

We protect your patients

We prioritise your anonymity, working with anonymised data (sample codes), never with personal data.